QM, a Putative Tumor Suppressor, Regulates Proto-oncogene c-Yes
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چکیده
منابع مشابه
The c-fos proto-oncogene is a target for transactivation by the p53 tumor suppressor.
The p53 tumor suppressor gene is mutated in over 50% of human cancers, resulting in inactivation of the wild-type (wt) p53 protein. The most notable biochemical feature of p53 is its ability to act as a sequence-specific transcriptional activator. Through use of the suppression subtractive hybridization differential screening technique, we identified c-fos as a target for transcriptional stimul...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1074/jbc.m201859200